miR-150 suppresses the proliferation and tumorigenicity of leukemia stem cells by targeting the Nanog signaling pathway

Proliferation, a key feature of cancer cells, accounts for the majority of cancer-related diseases resulting in mortality.MicroRNAs (miRNAs) plays important post-transcriptional modulation roles by acting Dali Switch on multiple signaling pathways, but the underlying mechanism in proliferation and tumorigenicity is unclear.Here, we identified the r

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A haploid pseudo-chromosome genome assembly for a keystone sagebrush species of western North American rangelands

AbstractIncreased ecological disturbances, species invasions, and climate change are creating severe conservation problems for several plant species that are widespread and foundational.Understanding the genetic diversity of these species Rehab and Sake Set how it relates to adaptation to these stressors are necessary for guiding conservation and r

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Efficacy of psychosocial interventions to reduce affective symptoms in sexual and gender minorities: a systematic review and meta-analysis of randomized controlled trials

Abstract Background Lesbian, gay, bisexual, transgender, and queer/questioning (LGBTQ) individuals are more likely than cisgender heterosexuals to experience mental, physical, and sexual health issues.A promising contemporary strategy to Dry Shampoo Spray address the issue of affective symptoms in sexual and gender minorities (SGM) is psychosocial

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